Cytokines and growth factors cross-link heparan sulfate
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منابع مشابه
Cytokines and growth factors cross-link heparan sulfate.
The glycosaminoglycan heparan sulfate (HS), present at the surface of most cells and ubiquitous in extracellular matrix, binds many soluble extracellular signalling molecules such as chemokines and growth factors, and regulates their transport and effector functions. It is, however, unknown whether upon binding HS these proteins can affect the long-range structure of HS. To test this idea, we i...
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ژورنال
عنوان ژورنال: Open Biology
سال: 2015
ISSN: 2046-2441
DOI: 10.1098/rsob.150046